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- MakaleAçık Erişim2025Scopus SJRQ1An overlooked connection: oral health status in patients with chronic diseases
Öçbe, Melisa; Çelebi, Elif; Öçbe, Çetin Batuhan
Background: Oral and systemic health are closely linked. Chronic diseases like diabetes mellitus, cardiovascular diseases, and hypertension increase the risk of dental caries, periodontal disease and tooth loss. Moreover, poor oral health can worsen the status of systemic diseases. Despite this, oral health is often overlooked in chronic disease management. This study aimed to evaluate the oral health status of patients with chronic diseases (PWCD) compared to healthy controls using DIMF-T and DMF-S indices. Methods: This retrospective study included 205 participants (106 PWCD and 99 healthy controls) attending the Oral Diagnosis & Radiology outpatient clinic at Bahçeşehir University Dental Hospital. Comprehensive intraoral and radiological examinations assessed caries lesions, missing teeth, filled teeth, periodontal disease, denture usage, and the prevalence of apical osteitis, soft tissue lesions, and intraosseous lesions. Oral health status was quantified using DIMF-T and DMF-S indices. Statistical analyses were conducted to identify differences between groups. Results: The study group (PWCD) exhibited significantly higher median values for missing teeth (MT), decayed surfaces (DS), missing surfaces (MS), DIMF-T, and DMF-S indices compared to the control group (p < 0.001). Chronic periodontitis was more prevalent in PWCD (76.42%) than in controls (45.45%), while gingivitis was more common in the control group (52.53%, p < 0.001). Medication use for systemic diseases was strongly associated with poor oral health outcomes (p < 0.001). However, no significant differences were observed between the groups for decayed teeth (DT), hopeless teeth (IT), or filled teeth (FT). Conclusions: PWCD demonstrated worse oral health outcomes compared to healthy controls, highlighting the need for integrated oral and systemic healthcare strategies. Dental professionals should be careful in identifying oral conditions that may signal underlying systemic diseases. Future research should explore the integration of oral health evaluations into routine medical screenings and examine the global practices of oral health management in PWCD.
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İncele - MakaleAçık Erişim2025Scopus SJRQ1Exploring the potential of interdental brush in oral cytology: a pilot study on sampling efficiency
Çelebi, Elif; Öçbe, Melisa; Sinanoğlu, Enver Alper; Tekkeşin, Merva Soluk
Background: With the renewed interest in brush biopsies, particularly for screening oral potentially malignant disorders and cancers, understanding the efficacy of available brush types in oral cytology is crucial. This study aims to compare the effectiveness of interdental brush sampling with commonly used cytology brushes in oral cytology evaluation. Methods: The study design was an observational clinical study. Brush biopsies were collected from the buccal mucosa of 99 healthy volunteers using an Interdental Brush- TePe Original Interdental Brush (TePe, Malmö, Sweden) (Cell sampling-Interdental Brush (CSIB)), Cytobrush Plus GT (Medscand Medical AB, Sweden) (Cell sampling device 1 (CSD1)), and CervexBrush (Rovers, Oss, Netherlands) (Cell sampling device 2 (CSD2)). Samples were evaluated for cellularity, depth of the epithelial layer, and cellular integrity. Results were compared between brush types using the Friedman test, and multiple comparisons were examined using the Dunn test. The significance level was set at p < 0.05. Results: Of the 99 cases, 59.6% were female and 40.4% were male, with a prevalence of smoking and alcohol consumption at 43.4%. The mean age was 24.3 years (± 4.5). There were no significant differences in cellularity between the brush types (p = 0.205). Mild cellularity was observed at rates of 3%, 9.1%, and 9.1% for CSD1, CSIB, and CSD2, respectively. Parabasal/basal layer cells were detected in 1% of samples collected with CSD1 and 4% with CSD2, while CSIB samples contained only superficial/intermediate cells. CSIB produced an inadequate integrity rate of 30.3%, whereas neither CSD2 nor CSD1 yielded samples with inadequate integrity. Conclusions: Interdental brushes may have potential as accessible and practical tools for chairside cytological screening. The CSIB obtained high-cellularity samples; however, it demonstrated low scores in cellular integrity. Future oral cytological studies may explore the modifications in interdental brush design to improve its potential in sampling for cell preservation and integrity.
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