Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ1Comparison of the effectiveness and safety of vaginal and sublingual low-dose misoprostol versus vaginal dinoprostone for labor ınduction: A retrospective cohort study
Eminov, Elmin; Eminov, Ayşe
Background Labor induction is one of the most common obstetric interventions, yet the optimal pharmacological agent and route of administration remain subjects of ongoing debate. Prostaglandin analogs such as misoprostol and dinoprostone are widely used for cervical ripening and induction; however, evidence comparing their effectiveness and safety across different routes is still limited. Aim The primary purpose of the study is to evaluate the efficacy and safety of vaginal and sublingual misoprostol and vaginal dinoprostone pessary in labor induction. Materials and Methods Patients were divided into three groups based on the labor induction methods used. The first group included patients who received 25 µg vaginal misoprostol for labor induction, the second group included patients who received 25 µg sublingual misoprostol, and the third group included patients who received vaginal dinoprostone pessary. The primary outcome of the study was to evaluate vaginal delivery rates and time from induction to delivery of the fetus. The secondary outcomes of the study were to evaluate cesarean delivery rates, indications for cesarean delivery, first- and fifth-minute Apgar scores, birth weight, gender, amniotic fluid meconium contamination, and admission rates to the neonatal intensive care unit (NICU). The study data were collected from the hospital’s automation system and archives. All patients’ demographic and obstetric characteristics and maternal and fetal outcomes were recorded in a spreadsheet document (Microsoft Excel™), and statistical analyses were performed using the SPSS 28.0 program. Results Vaginal delivery rates were higher in the group where vaginal (86,5%) and sublingual misoprostol (85,3%) were applied, and cesarean delivery rates were higher in the group where vaginal dinoprostone pessary (31,6%) was applied (p=0.000). When the groups were compared according to the duration of labor, no difference was found in the vaginal (523.86±405,92) and sublingual misoprostol (560.15±438,00) groups, while the duration of labor was significantly higher in the dinoprostone pessary group (857.37±558,36) (p=0.000). Hyperstimulation (6.8%) (p=0.007) and admission rates to the neonatal intensive care unit (9.1%) (p=0.004) were higher in the dinoprostone group, and this difference was statistically significant. Conclusion According to the results of the study, low-dose vaginal or sublingual misoprostol was found to be more effective and safer than vaginal dinoprostone pessary in labor induction.
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İncele - MakaleYayıncıda açık erişim2025Scopus SJRQ1Prevalence of adolescent pregnancy and evaluation of pregnancy outcomes: a retrospective study
Eminov, Elmin; Eminov, Ayşe
Introduction: According to the World Health Organization, adolescent pregnancy is defined as pregnancies of women aged 19 and below. The study aims to analyze the rates of adolescent pregnancies and maternal and fetal outcomes among births within the hospital and compare them with adult pregnancies. Methods: The study is conducted retrospectively in one of Turkey’s socio-economically underdeveloped provinces. The study comprises 16,985 women: 1719 adolescents and 15,266 adults who gave birth in the hospital between January 1, 2020, and December 31, 2023. All data were recorded in the SPSS 28.0 program, and the Kolmogorov–Smirnov test, Chi-Square test, ANOVA, and Independent Simple T-test were applied to analyze the data. Results: In the study, the adolescent pregnancy rate is found to be 10,1%. The mean maternal age (p = 0.000), gravida (p = 0.000), parity (p = 0.000), and number of abortions (p = 0.002) are significantly higher in the adult group. No difference is found between the groups in terms of gestational age (p = 0.067). Newborn birth weight was significantly higher in the adult group (p = 0.000). Cesarean section rates are higher in the adult group (p = 0.001). No difference is found in terms of stillbirth rates. No difference is found between the groups in terms of pre-eclampsia (p = 0.792). No difference is found between the groups in terms of preterm birth (p = 0.664). Conclusion: In conclusion, it came out that, according to the results of the study, the rates of premature birth, pre-eclampsia, and stillbirth in adolescents and the first and fifth-minute Apgar scores are similar to adults. However, newborn birth weights are lower in the babies of adolescent pregnant women. In addition, cesarean section rates are higher in the adult group.
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