Clinical development of quinone-based drugs

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This chapter provides a detailed explanation of the clinical investigations, pharmacological effects, and characteristics of quinone and quinone derivatives, along with references to pertinent sources. Although quinones have an oxygen group in their structure, they are quickly oxidized and interact with reactive oxygen species. This demonstrates how quinones work as drugs. Quinones and their derivatives are used as medications to treat a wide range of diseases, including cancer, lung, kidney, brain, and tumor disorders. Each of the following has effects on a different area of health; lapochols, anthraquinones, naphthoquinone and its derivatives, and other wide range of quinone derivatives are thoroughly explored in this chapter.

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AlanDeğerDil
dc.contributor.authorAltuner, Elif Esra
dc.contributor.authorIssa, Ghassan
dc.contributor.authorOzalp, Veli Cengİz
dc.contributor.authorAldemir, Ozan
dc.contributor.authorTorlak, Yasemin
dc.contributor.authorDar, Umar Ali
dc.date.accessioned2026-10-27T23:47:28.202079028Z
dc.date.available2026-10-27T23:47:28.202079028Z
dc.date.issued2024
dc.description.abstractThis chapter provides a detailed explanation of the clinical investigations, pharmacological effects, and characteristics of quinone and quinone derivatives, along with references to pertinent sources. Although quinones have an oxygen group in their structure, they are quickly oxidized and interact with reactive oxygen species. This demonstrates how quinones work as drugs. Quinones and their derivatives are used as medications to treat a wide range of diseases, including cancer, lung, kidney, brain, and tumor disorders. Each of the following has effects on a different area of health; lapochols, anthraquinones, naphthoquinone and its derivatives, and other wide range of quinone derivatives are thoroughly explored in this chapter.
dc.identifier.doi10.1016/b978-0-443-24126-0.00018-4
dc.identifier.endpage310
dc.identifier.isbn978-044324126-0
dc.identifier.isbn978-044324125-3
dc.identifier.scopus2-s2.0-85211860746
dc.identifier.startpage301
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/kostu/10380
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofQuinone-Based Compounds in Drug Discovery: Trends and Applications
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDrug effects
dc.subjectMedicine
dc.subjectQuinone derivatives
dc.subjectQuinones
dc.subjectQuinones in medicine
dc.titleClinical development of quinone-based drugs
dc.typeBook Chapter
rdl.citation.openalex0
rdl.citation.scopus0
rdl.oa.statusclosed
rdl.sdgSDG03
rdl.source.indexSCOPUS